InfiniVive MD Exosomes
contains exosomes, cytokines, growth factors, vitamins, trace elements, secretomes, and antioxidants. Exosomes are extracellular vesicular nanostructures, containing proteins, mRNA, microRNA, and other substances. They have a diameter of 20-100nm and are secreted by most cells.
Exosomes are involved in cellular communication, immune function, development and differentiation of stem cells, neuronal function, tissue regeneration, and intercellular macromolecular transport.
InfiniVive Exosomes Potency
Exosomes can be derived from a number of cells. Our comparative analysis of multiple cell lines demonstrates significantly greater potency of umbilical cord-derived mesenchymal stem cells as compared to adipose, placental, and bone marrow cells. Infinivive MD Exosome Serum is derived from the most potent cells available.
InfiniVive Exosome Serum Purity
While there is no definitive way of identifying exosomes, Infinivive MD uses a multimodality process to quantify and qualify InfiniVive MD Exosome Serum. From concentration to purity, to phenotype, InfiniVive MD outperforms all others.
In a comparative analysis, InfiniVive MD Exosome Serum was found to have greater than 95% purity — as much as 800% greater than other products tested.
Phenotypic Analysis
InfiniVive MD shows high medium flourescent intensity (MFI) while other products had no expression of vital protein surface markers.
Important Markers of InfiniVive MD Exosomes
CD-9 has a diverse role in cellular communication. It is suggested that CD-9 is involved in the modulation of cellular adhesion and migration. Studies have shown CD-9 to help block viral entry into cells and to block the adhesion of bacteria such as Staphylococcus aureus to wounds.
CD-63 has a role in platelet activation, promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading, and migration. This protein also plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes.
CD-81 has been shown to be involved in the recruitment of numerous adhesion molecules, receptors, and signaling proteins in the central zone of the immune response. Apart from its structural role, CD-81 also delivers a co-signal for T cells to trigger cytokine production and cellular proliferation, thus suggesting a key role in biological functions.